2021
Sabaté M, Vidal X, Ballarin E, Rottenkolber M, Schmiedl S, Grave B, Huerta C, Martin-Merino E, Montero D, Leon-Muñoz LM, Gasse C, Moore N, Droz C, Lassalle R, Aakjær M, Andersen M, De Bruin ML, Souverein P, Klungel OH, Gardarsdottir H, Ibáñez L. (2021). Adherence to Direct Oral Anticoagulants in Patients With Non-Valvular Atrial Fibrillation: A Cross-National Comparison in Six European Countries (2008–2015). Frontiers in Pharmacology. 2021;12:2116. https://doi:10.3389/fphar.2021.682890
González-Bermejo D, Castillo-Cano B, Rodríguez-Pascual A, et al. Effect of regulatory interventions on agomelatine use in Spain: a multiple intervention time-series analysis in a nationwide electronic healthcare record database [published online ahead of print, 2021 Oct 22]. Pharmacoepidemiol Drug Saf. 2021;10.1002/pds.5374. https://doi:10.1002/pds.5374.
de Abajo FJ, Rodríguez-Martín S, Barreira D, et al. Influenza vaccine and risk of acute myocardial infarction in a population-based case-control study [published online ahead of print, 2021 Oct 13]. Heart. 2021;heartjnl-2021-319754. https://doi:10.1136/heartjnl-2021-319754.
Rodríguez-Espinosa N, González-Colaço Harmand M, Miranda Saavedra F, et al. Prescripción de inhibidores de acetilcolinesterasa y memantina en Canarias: comparación con la población española [Prescription of acetylcholinesterase inhibitors and memantine in the Canary Islands, comparison with the Spanish population.]. Rev Esp Salud Publica. 2021;95:e202109125. Published 2021 Sep 24.
de Burgos-Gonzalez, A., Bryant, V., Maciá-Martinez, M. A., & Huerta, C. (2021). A strategy for assessment and validation of major bleeding cases in a primary health care database in Spain. Pharmacoepidemiology and drug safety, 10.1002/pds.5357. Advance online publication. https://doi.org/10.1002/pds.5357
de Bont, J., Bennett, M., León-Muñoz, L. M., & Duarte-Salles, T. (2021). The prevalence and incidence rate of overweight and obesity among 2.5 million children and adolescents in Spain. Revista española de cardiología (English ed.), S1885-5857(21)00216-4. Advance online publication. https://doi.org/10.1016/j.rec.2021.07.002
Mazzucchelli, R., Rodríguez-Martín, S., García-Vadillo, A., Gil, M., Rodríguez-Miguel, A., Barreira-Hernández, D., García-Lledó, A., & de Abajo, F. J. (2021). Risk of acute myocardial infarction among new users of chondroitin sulfate: A nested case-control study. PloS one, 16(7), e0253932. https://doi.org/10.1371/journal.pone.0253932
Royé, D., Tobías, A., Figueiras, A., Gestal, S., Taracido, M., Santurtun, A., & Iñiguez, C. (2021). Temperature-related effects on respiratory medical prescriptions in Spain. Environmental research, 202, 111695. Advance online publication. https://doi.org/10.1016/j.envres.2021.111695
van den Ham, H. A., Souverein, P. C., Klungel, O. H., Platt, R. W., Ernst, P., Dell'Aniello, S., Schmiedl, S., Grave, B., Rottenkolber, M., Huerta, C., Martín Merino, E., León-Muñoz, L. M., Montero, D., Andersen, M., Aakjaer, M., De Bruin, M. L., & Gardarsdottir, H. (2021). Major bleeding in users of direct oral anticoagulants in atrial fibrillation: A pooled analysis of results from multiple population-based cohort studies. Pharmacoepidemiology and drug safety, 30(10), 1339–1352. https://doi.org/10.1002/pds.5317
Martín-Merino, E., Castillo-Cano, B., Martín-Perez, M., Llorente-García, A., & Montero-Corominas, D. (2021). Papillomavirus vaccination and Guillain-Barre Syndrome among girls: A cohort study in Spain. Vaccine, 39(31), 4306–4313. https://doi.org/10.1016/j.vaccine.2021.06.029
Sanchez Ortiz, S., Huerta, C., Llorente-García, A., Ortega, P., Astasio, P., & Cea-Soriano, L. (2021). A Validation Study on the Frequency and Natural History of Miscarriages Using the Spanish Primary Care Database BIFAP. Healthcare (Basel, Switzerland), 9(5), 596. https://doi.org/10.3390/healthcare9050596
León-Muñoz, L. M., Duarte-Salles, T., Llorente, A., Díaz, Y., Puente, D., Pottegård, A., Montero-Corominas, D., & Huerta, C. (2021). Use of hydrochlorothiazide and risk of skin cancer in a large nested case-control study in Spain. Pharmacoepidemiology and drug safety, 30(9), 1269–1278. https://doi.org/10.1002/pds.5295
Hernández-Rodríguez, M. Á., Sempere-Verdú, E., Vicens-Caldentey, C., González-Rubio, F., Miguel-García, F., Palop-Larrea, V., Orueta-Sánchez, R., Esteban-Jiménez, Ó., Sempere-Manuel, M., Arroyo-Aniés, M. P., Fernández-San José, B., de Juan-Roldán, J. I., & Ioakeim-Skoufa, I. (2021). Drug Prescription Profiles in Patients with Polypharmacy in Spain: A Large-Scale Pharmacoepidemiologic Study Using Real-World Data. International journal of environmental research and public health, 18(9), 4754. https://doi.org/10.3390/ijerph18094754
Sultana, J., Trotta, F., Addis, A., Brown, J. S., Gil, M., Menniti-Ippolito, F., Milozzi, F., Suissa, S., & Trifirò, G. (2020). Healthcare Database Networks for Drug Regulatory Policies: International Workshop on the Canadian, US and Spanish Experience and Future Steps for Italy. Drug safety, 43(1), 1–5. https://doi.org/10.1007/s40264-019-00871-w
Martín-Merino E, Molina-Infante J, Martín-Pérez M, Castillo-Cano B, Montero-Corominas D. Updated Incidence of Inflammatory Bowel Disease
Among Girls Attended in the Spanish Public Health System. Ann Pediatr. 2021; 4(1): 1058. https://meddocsonline.org/annals-of-pediatrics/updated-incidence-of-inflammatory-bowel-disease-among-girls-attended-in-the-spanish-public.pdf
Martín-Merino, E., Castillo-Cano, B., Martín-Pérez, M., Llorente-García, A., & Montero-Corominas, D. (2021). Evaluation of the Risk of Inflammatory Bowel Disease after the HPV Vaccination in Primary Care in Spain: A Time-Varying Cohort Analysis of Around 390,000 Girls. Drug safety, 44(4), 455–466. https://doi.org/10.1007/s40264-020-01040-0
Willame, C., Dodd, C., van der Aa, L., Picelli, G., Emborg, H. D., Kahlert, J., Gini, R., Huerta, C., Martín-Merino, E., McGee, C., de Lusignan, S., Roberto, G., Villa, M., Weibel, D., Titievsky, L., & Sturkenboom, M. (2021). Incidence Rates of Autoimmune Diseases in European Healthcare Databases: A Contribution of the ADVANCE Project. Drug safety, 44(3), 383–395. https://doi.org/10.1007/s40264-020-01031-1
2020
Bollaerts, K., Ledent, E., de Smedt, T., Weibel, D., Emborg, H. D., Danieli, G., Duarte-Salles, T., Huerta-Alvarez, C., Martín-Merino, E., Picelli, G., Tramontan, L., Sturkenboom, M., & Bauchau, V. (2020). ADVANCE system testing: Benefit-risk analysis of a marketed vaccine using multi-criteria decision analysis and individual-level state transition modelling. Vaccine, 38 Suppl 2, B65–B75. https://doi.org/10.1016/j.vaccine.2019.09.034
Dodd, C., de Ridder, M., Weibel, D., Mahaux, O., Haguinet, F., de Smedt, T., de Lusignan, S., McGee, C., Duarte-Salles, T., Emborg, H. D., Huerta-Alvarez, C., Martín-Merino, E., Picelli, G., Berencsi, K., Danieli, G., & Sturkenboom, M. (2020). ADVANCE system testing: Estimating the incidence of adverse events following pertussis vaccination in healthcare databases with incomplete exposure data. Vaccine, 38 Suppl 2, B47–B55. https://doi.org/10.1016/j.vaccine.2020.03.050
Mazzucchelli, R., Rodríguez-Martín, S., García-Vadillo, A., Crespí-Villarías, N., Gil, M., Rodriguez-Miguel, A., Barreira, D., Garcia-Lledó, A., & de Abajo, F. J. (2020). Risk of acute myocardial infarction among new users of bisphosphonates: a nested case-control study. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 31(12), 2403–2412. https://doi.org/10.1007/s00198-020-05538-2
Rodríguez-Martín, S., García-Lledó, A., Gil, M., Barreira-Hernández, D., Rodríguez-Miguel, A., & de Abajo, F. J. (2020). Prescription prevalence of low dose aspirin in primary prevention in the Spanish population, trends over time and associated factors. Prevalencia de prescripción del ácido acetilsalicílico a dosis bajas en prevención primaria en población española, evolución temporal y factores asociados. Medicina clínica, 155(3), 104–111. https://doi.org/10.1016/j.medcli.2019.10.012
Martín-Merino, E., Moreno-Juste, A., Castillo Cano, B., Martín Pérez, M., & Montero Corominas, D. (2021). An Estimation of the Incidence of Thyroiditis Among Girls in Primary Care in Spain. Journal of clinical research in pediatric endocrinology, 13(2), 170–179. https://doi.org/10.4274/jcrpe.galenos.2020.2020.0225
González-Bermejo, D., Rayón-Iglesias, P., Rodríguez-Pascual, A., Álvarez-Gutiérrez, A., Fernández-Dueñas, A., Montero-Corominas, D., & Huerta-Álvarez, C. (2021). Drug utilization study on immediate release Fentanyl in Spain. Prevalence, incidence, and indication. Pharmacoepidemiology and drug safety, 30(3), 371–378. https://doi.org/10.1002/pds.5118
Martín-Merino, E., Martín-Pérez, M., Castillo-Cano, B., & Montero-Corominas, D. (2020). The recording and prevalence of Inflammatory bowel disease in girls' primary care medical Spanish records. Pharmacoepidemiology and drug safety, 29(11), 1440–1449. https://doi.org/10.1002/pds.5107
Alqdwah-Fattouh, R., Rodríguez-Martín, S., de Abajo, F. J., González-Bermejo, D., Gil, M., García-Lledó, A., & Bolúmar, F. (2020). Differential effects of antidepressant subgroups on risk of acute myocardial infarction: A nested case-control study. British journal of clinical pharmacology, 86(10), 2040–2050. https://doi.org/10.1111/bcp.14299
Souverein, P. C., van den Ham, H. A., Huerta, C., Merino, E. M., Montero, D., León-Muñoz, L. M., Schmiedl, S., Heeke, A., Rottenkolber, M., Andersen, M., Aakjaer, M., De Bruin, M. L., Klungel, O. H., & Gardarsdottir, H. (2021). Comparing risk of major bleeding between users of different oral anticoagulants in patients with nonvalvular atrial fibrillation. British journal of clinical pharmacology, 87(3), 988–1000. https://doi.org/10.1111/bcp.14450
Arias Fernández, L., Pardo Seco, J., Cebey-López, M., Gil Prieto, R., Rivero-Calle, I., Martinon-Torres, F., Gil de Miguel, Á., NEUMOEXPERTOS group, Martinón-Torres, F., Vargas, D., Mascarós, E., Redondo, E., Díaz-Maroto, J. L., Linares-Rufo, M., Gil, A., Molina, J., Ocaña, D., & Rivero-Calle, I. (2019). Differences between diabetic and non-diabetic patients with community-acquired pneumonia in primary care in Spain. BMC infectious diseases, 19(1), 973. https://doi.org/10.1186/s12879-019-4534-x
Aldaz, P., Garjón, J., Beitia, G., Beltrán, I., Librero, J., Ibáñez, B., Arroyo, P., & Ariz, M. J. (2021). Association between benzodiazepine use and development of dementia. Medicina clinica, 156(3), 107–111. https://doi.org/10.1016/j.medcli.2020.02.006
de Abajo, F. J., Rodríguez-Martín, S., Lerma, V., Mejía-Abril, G., Aguilar, M., García-Luque, A., Laredo, L., Laosa, O., Centeno-Soto, G. A., Ángeles Gálvez, M., Puerro, M., González-Rojano, E., Pedraza, L., de Pablo, I., Abad-Santos, F., Rodríguez-Mañas, L., Gil, M., Tobías, A., Rodríguez-Miguel, A., Rodríguez-Puyol, D., … MED-ACE2-COVID19 study group (2020). Use of renin-angiotensin-aldosterone system inhibitors and risk of COVID-19 requiring admission to hospital: a case-population study. Lancet (London, England), 395(10238), 1705–1714. https://doi.org/10.1016/S0140-6736(20)31030-8
Maciá-Martínez, M. A., Gil, M., Huerta, C., Martín-Merino, E., Álvarez, A., Bryant, V., Montero, D., & BIFAP Team (2020). Base de Datos para la Investigación Farmacoepidemiológica en Atención Primaria (BIFAP): A data resource for pharmacoepidemiology in Spain. Pharmacoepidemiology and drug safety, 29(10), 1236–1245. https://doi.org/10.1002/pds.5006
Braeye, T., Emborg, H. D., Llorente-García, A., Huerta, C., Martín-Merino, E., Duarte-Salles, T., Danieli, G., Tramontan, L., Weibel, D., McGee, C., Villa, M., Gini, R., Lehtinen, M., Titievsky, L., & Sturkenboom, M. (2020). Age-specific vaccination coverage estimates for influenza, human papillomavirus and measles containing vaccines from seven population-based healthcare databases from four EU countries - The ADVANCE project. Vaccine, 38(16), 3243–3254. https://doi.org/10.1016/j.vaccine.2020.02.082
Saiz, L. C., Gil, M., Alonso, A., Erviti, J., Garjón, J., & Martínez, M. (2020). Use of methylphenidate and risk for valvular heart disease: A case-control study nested in the BIFAP cohort. Pharmacoepidemiology and drug safety, 29(3), 288–295. https://doi.org/10.1002/pds.4954
Hernández-Rodríguez, M. Á., Sempere-Verdú, E., Vicens-Caldentey, C., González-Rubio, F., Miguel-García, F., Palop-Larrea, V., Orueta-Sánchez, R., Esteban-Jiménez, Ó., Sempere-Manuel, M., Arroyo-Aniés, M. P., & Fernández-San José, B. (2020). Evolution of polypharmacy in a spanish population (2005-2015): A database study. Pharmacoepidemiology and drug safety, 29(4), 433–443. https://doi.org/10.1002/pds.4956
Requena, G., Douglas, I. J., Huerta, C., & de Abajo, F. (2020). Impact of pre-exposure time bias in self-controlled case series when the event conditions the exposure: Hip/femur fracture and use of benzodiazepines as a case study. Pharmacoepidemiology and drug safety, 29(4), 388–395. https://doi.org/10.1002/pds.4959
2019
Rodríguez-Martín, S., de Abajo, F. J., Gil, M., González-Bermejo, D., Rodríguez-Miguel, A., Barreira-Hernández, D., Mazzucchelli, R., García-Lledó, A., & García-Rodríguez, L. A. (2019). Risk of Acute Myocardial Infarction Among New Users of Allopurinol According to Serum Urate Level: A Nested Case-Control Study. Journal of clinical medicine, 8(12), 2150. https://doi.org/10.3390/jcm8122150
Sanchez Ortiz, S., Llorente García, A., Astasio, P., Huerta, C., & Cea Soriano, L. (2020). An algorithm to identify pregnancies in BIFAP Primary Care database in Spain: Results from a cohort of 155 419 pregnancies. Pharmacoepidemiology and drug safety, 29(1), 57–68. https://doi.org/10.1002/pds.4910
Rodríguez-Martín, S., Martín-Merino, E., Lerma, V., Rodríguez-Miguel, A., González, O., González-Herrada, C., Ramírez, E., Bellón, T., & de Abajo, F. J. (2019). Incidence of Stevens-Johnson syndrome/toxic epidermal necrolysis among new users of different individual drugs in a European population: a case-population study. European journal of clinical pharmacology, 75(2), 237–246. https://doi.org/10.1007/s00228-018-2569-3
Martín-Merino, E., Llorente-García, A., Castillo Cano, B., Montero Corominas, D., & Huerta-Álvarez, C. (2019). The Longitudinal Incidence of Human Papillomavirus Vaccination in Spanish Primary Care in the First 10 Years After Approval. Pharmaceutical medicine, 33(6), 519–530. https://doi.org/10.1007/s40290-019-00309-9
Braeye, T., Bauchau, V., Sturkenboom, M., Emborg, H. D., García, A. L., Huerta, C., Merino, E. M., & Bollaerts, K. (2019). Estimation of vaccination coverage from electronic healthcare records; methods performance evaluation - A contribution of the ADVANCE-project. PloS one, 14(9), e0222296. https://doi.org/10.1371/journal.pone.0222296
Emborg, H. D., Kahlert, J., Braeye, T., Bauwens, J., Bollaerts, K., Danieli, G., Duarte-Salles, T., Glismann, S., Huerta-Alvarez, C., de Lusignan, S., Martín-Merino, E., McGee, C., Correa, A., Tramontan, L., Weibel, D., & Sturkenboom, M. (2020). ADVANCE system testing: Can coverage of pertussis vaccination be estimated in European countries using electronic healthcare databases: An example. Vaccine, 38 Suppl 2, B22–B30. https://doi.org/10.1016/j.vaccine.2019.07.039
Weibel, D., Dodd, C., Mahaux, O., Haguinet, F., De Smedt, T., Duarte-Salles, T., Picelli, G., Tramontan, L., Danieli, G., Correa, A., McGee, C., Martín-Merino, E., Huerta-Alvarez, C., Berencsi, K., Emborg, H. D., Bollaerts, K., Bauchau, V., Titievsky, L., & Sturkenboom, M. (2020). ADVANCE system testing: Can safety studies be conducted using electronic healthcare data? An example using pertussis vaccination. Vaccine, 38 Suppl 2, B38–B46. https://doi.org/10.1016/j.vaccine.2019.06.040
Tin Tin Htar, M., de Ridder, M., Braeye, T., Correa, A., McGee, C., de Lusignan, S., Duarte-Salles, T., Huerta-Alvarez, C., Martín-Merino, E., Tramontan, L., Danieli, G., Picelli, G., van der Maas, N., Berencsi, K., Arnheim-Dahlström, L., Heininger, U., Emborg, H. D., Weibel, D., Bollaerts, K., & Sturkenboom, M. (2020). Advance system testing: Vaccine benefit studies using multi-country electronic health data - The example of pertussis vaccination. Vaccine, 38 Suppl 2, B31–B37. https://doi.org/10.1016/j.vaccine.2019.08.078
Gini, R., Dodd, C. N., Bollaerts, K., Bartolini, C., Roberto, G., Huerta-Alvarez, C., Martín-Merino, E., Duarte-Salles, T., Picelli, G., Tramontan, L., Danieli, G., Correa, A., McGee, C., Becker, B., Switzer, C., Gandhi-Banga, S., Bauwens, J., van der Maas, N., Spiteri, G., Sdona, E., … Sturkenboom, M. (2020). Quantifying outcome misclassification in multi-database studies: The case study of pertussis in the ADVANCE project. Vaccine, 38 Suppl 2, B56–B64. https://doi.org/10.1016/j.vaccine.2019.07.045
Rivero-Calle, I., Cebey-López, M., Pardo-Seco, J., Yuste, J., Redondo, E., Vargas, D. A., Mascarós, E., Díaz-Maroto, J. L., Linares-Rufo, M., Jimeno, I., Gil, A., Molina, J., Ocaña, D., & Martinón-Torres, F. (2019). Lifestyle and comorbid conditions as risk factors for community-acquired pneumonia in outpatient adults (NEUMO-ES-RISK project). BMJ open respiratory research, 6(1), e000359. https://doi.org/10.1136/bmjresp-2018-000359
Gil, M., González-González, R., Vázquez-Calvo, A., Álvarez-Gutiérrez, A., Martín-Acebes, M. A., Praena, B., Bello-Morales, R., Saiz, J. C., López-Guerrero, J. A., Tabarés, E., & Sobrino, F. (2019). Clinical Infections by Herpesviruses in Patients Treated with Valproic Acid: A Nested Case-Control Study in the Spanish Primary Care Database, BIFAP. Journal of clinical medicine, 8(9), 1442. https://doi.org/10.3390/jcm8091442
Aguilar-Shea, A. L., & Bonis, J. (2019). COPD from an everyday primary care point of view. Journal of family medicine and primary care, 8(8), 2644–2650. https://doi.org/10.4103/jfmpc.jfmpc_477_19
Martín-Merino, E., Llorente-García, A., Montero-Corominas, D., & Huerta, C. (2019). The recording of human papillomavirus (HPV) vaccination in BIFAP primary care database: A validation study. Pharmacoepidemiology and drug safety, 28(2), 201–208. https://doi.org/10.1002/pds.4674
Hedenmalm, K., Blake, K., Donegan, K., Macia, M. A., Gil, M., Williams, J., Montero, D., Candore, G., Morales, D., Kurz, X., & Arlett, P. (2019). A European multicentre drug utilisation study of the impact of regulatory measures on prescribing of codeine for pain in children. Pharmacoepidemiology and drug safety, 28(8), 1086–1096. https://doi.org/10.1002/pds.4836
Rodríguez-Miguel, A., García-Rodríguez, L. A., Gil, M., Barreira-Hernández, D., Rodríguez-Martín, S., & de Abajo, F. J. (2019). Population-based case-control study: chemoprotection of colorectal cancer with non-aspirin nonsteroidal anti-inflammatory drugs and other drugs for pain control. Alimentary pharmacology & therapeutics, 50(3), 295–305. https://doi.org/10.1111/apt.15333
Gil, M., Rodríguez-Miguel, A., Montoya-Catalá, H., González-González, R., Álvarez-Gutiérrez, A., Rodríguez-Martín, S., García-Rodríguez, L. A., & de Abajo, F. J. (2019). Validation study of colorectal cancer diagnosis in the Spanish primary care database, BIFAP. Pharmacoepidemiology and drug safety, 28(2), 209–216. https://doi.org/10.1002/pds.4686
2018
Raman, S. R., Man, K., Bahmanyar, S., Berard, A., Bilder, S., Boukhris, T., Bushnell, G., Crystal, S., Furu, K., KaoYang, Y. H., Karlstad, Ø., Kieler, H., Kubota, K., Lai, E. C., Martikainen, J. E., Maura, G., Moore, N., Montero, D., Nakamura, H., Neumann, A., … Wong, I. (2018). Trends in attention-deficit hyperactivity disorder medication use: a retrospective observational study using population-based databases. The lancet. Psychiatry, 5(10), 824–835. https://doi.org/10.1016/S2215-0366(18)30293-1
Rodríguez-Martín, S., Martín-Merino, E., Lerma, V., Rodríguez-Miguel, A., González, O., González-Herrada, C., Ramírez, E., Bellón, T., & de Abajo, F. J. (2018). Active surveillance of severe cutaneous adverse reactions: A case-population approach using a registry and a health care database. Pharmacoepidemiology and drug safety, 27(9), 1042–1050. https://doi.org/10.1002/pds.4622
Martín-Merino, E., Calderón-Larrañaga, A., Hawley, S., Poblador-Plou, B., Llorente-García, A., Petersen, I., & Prieto-Alhambra, D. (2018). The impact of different strategies to handle missing data on both precision and bias in a drug safety study: a multidatabase multinational population-based cohort study. Clinical epidemiology, 10, 643–654. https://doi.org/10.2147/CLEP.S154914
Martín-Merino, E., Petersen, I., Hawley, S., Álvarez-Gutierrez, A., Khalid, S., Llorente-Garcia, A., Delmestri, A., Javaid, M. K., Van Staa, T. P., Judge, A., Cooper, C., & Prieto-Alhambra, D. (2018). Risk of venous thromboembolism among users of different anti-osteoporosis drugs: a population-based cohort analysis including over 200,000 participants from Spain and the UK. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 29(2), 467–478. https://doi.org/10.1007/s00198-017-4308-5
2017
de Abajo, F. J., Rodríguez-Martín, S., Rodríguez-Miguel, A., & Gil, M. J. (2017). Risk of Ischemic Stroke Associated With Calcium Supplements With or Without Vitamin D: A Nested Case-Control Study.
Journal of the American Heart Association, 6(5), e005795.
https://doi.org/10.1161/JAHA.117.005795
Saiz, L. C., Garjón, J., Gorricho, J., Erviti, J., Gil-García, M. J., & Martín-Merino, E. (2017). Validation and incidence of community-acquired pneumonia in patients with type 2 diabetes in the BIFAP database.
Epidemiology and infection, 145(14), 3056–3064.
https://doi.org/10.1017/S0950268817001868
Martín-Merino, E., Huerta-Álvarez, C., Prieto-Alhambra, D., Álvarez-Gutiérrez, A., & Montero-Corominas, D. (2017). Secular trends of use of anti-osteoporotic treatments in Spain: A population-based cohort study including over 1.5million people and more than 12years of follow-up.
Bone, 105, 292–298.
https://doi.org/10.1016/j.bone.2017.08.031
Gorricho, J., Garjón, J., Alonso, A., Celaya, M. C., Saiz, L. C., Erviti, J., & López, A. (2017). Use of oral antidiabetic agents and risk of community-acquired pneumonia: a nested case-control study.
British journal of clinical pharmacology, 83(9), 2034–2044.
https://doi.org/10.1111/bcp.13288
Martín-Merino, E., Huerta-Álvarez, C., Prieto-Alhambra, D., & Montero-Corominas, D. (2017). Cessation rate of anti-osteoporosis treatments and risk factors in Spanish primary care settings: a population-based cohort analysis.
Archives of osteoporosis, 12(1), 39.
https://doi.org/10.1007/s11657-017-0331-6
2016
Brauer, R., Ruigómez, A., Downey, G., Bate, A., Garcia Rodriguez, L. A., Huerta, C., Gil, M., de Abajo, F., Requena, G., Alvarez, Y., Slattery, J., de Groot, M., Souverein, P., Hesse, U., Rottenkolber, M., Schmiedl, S., de Vries, F., Tepie, M. F., Schlienger, R., Smeeth, L., Douglas, I., Reynolds, R., and Klungel, O. (2016) Prevalence of antibiotic use: a comparison across various European health care data sources.
Pharmacoepidemiol Drug Saf, 25, 11– 20.
https://doi.org/10.1002/pds.3831
Requena, G., Huerta, C., Gardarsdottir, H., Logie, J., González-González, R., Abbing-Karahagopian, V., Miret, M., Schneider, C., Souverein, P. C., Webb, D., Afonso, A., Boudiaf, N., Martin, E., Oliva, B., Alvarez, A., De Groot, M. C., Bate, A., Johansson, S., Schlienger, R., Reynolds, R., … de Abajo, F. J. (2016). Hip/femur fractures associated with the use of benzodiazepines (anxiolytics, hypnotics and related drugs): a methodological approach to assess consistencies across databases from the PROTECT-EU project.
Pharmacoepidemiology and drug safety, 25 Suppl 1, 66–78.
https://doi.org/10.1002/pds.3816
Requena, G., Logie, J., Martin, E., Boudiaf, N., González González, R., Huerta, C., Alvarez, A., Webb, D., Bate, A., García Rodríguez, L. A., Reynolds, R., Schlienger, R., Gardarsdottir, H., de Groot, M., Klungel, O. H., de Abajo, F., & Douglas, I. J. (2016). Do case-only designs yield consistent results across design and different databases? A case study of hip fractures and benzodiazepines.
Pharmacoepidemiology and drug safety, 25 Suppl 1(Suppl Suppl 1), 79–87.
https://doi.org/10.1002/pds.3822
Udo, R., Tcherny-Lessenot, S., Brauer, R., Dolin, P., Irvine, D., Wang, Y., Auclert, L., Juhaeri, J., Kurz, X., Abenhaim, L., Grimaldi, L., & De Bruin, M. L. (2016). The risk of acute liver injury associated with the use of antibiotics--evaluating robustness of results in the pharmacoepidemiological research on outcomes of therapeutics by a European consortium (PROTECT) project.
Pharmacoepidemiology and drug safety, 25 Suppl 1, 47–55.
https://doi.org/10.1002/pds.3841
Uddin, M. J., Groenwold, R. H., de Boer, A., Gardarsdottir, H., Martin, E., Candore, G., Belitser, S. V., Hoes, A. W., Roes, K. C., & Klungel, O. H. (2016). Instrumental variables analysis using multiple databases: an example of antidepressant use and risk of hip fracture.
Pharmacoepidemiology and drug safety, 25 Suppl 1, 122–131.
https://doi.org/10.1002/pds.3863
Ali, M. S., Groenwold, R. H., Belitser, S. V., Souverein, P. C., Martín, E., Gatto, N. M., Huerta, C., Gardarsdottir, H., Roes, K. C., Hoes, A. W., de Boer, A., & Klungel, O. H. (2016). Methodological comparison of marginal structural model, time-varying Cox regression, and propensity score methods: the example of antidepressant use and the risk of hip fracture.
Pharmacoepidemiology and drug safety, 25 Suppl 1, 114–121.
https://doi.org/10.1002/pds.3864
Huerta, C., Abbing-Karahagopian, V., Requena, G., Oliva, B., Alvarez, Y., Gardarsdottir, H., Miret, M., Schneider, C., Gil, M., Souverein, P. C., De Bruin, M. L., Slattery, J., De Groot, M. C., Hesse, U., Rottenkolber, M., Schmiedl, S., Montero, D., Bate, A., Ruigomez, A., García-Rodríguez, L. A., … de Abajo, F. J. (2016). Exposure to benzodiazepines (anxiolytics, hypnotics and related drugs) in seven European electronic healthcare databases: a cross-national descriptive study from the PROTECT-EU Project.
Pharmacoepidemiology and drug safety, 25 Suppl 1, 56–65.
https://doi.org/10.1002/pds.3825
de Hoyos-Alonso, M. C., Bonis, J., Tapias-Merino, E., Castell, M. V., & Otero, A. (2016). Estimated prevalence of dementia based on analysis of drug databases in the Region of Madrid (Spain).
Neurología (Barcelona, Spain), 31(1), 1–8.
https://doi.org/10.1016/j.nrl.2014.08.008
Brauer, R., Douglas, I., Garcia Rodriguez, L. A., Downey, G., Huerta, C., de Abajo, F., Bate, A., Feudjo Tepie, M., de Groot, M. C., Schlienger, R., Reynolds, R., Smeeth, L., Klungel, O., & Ruigómez, A. (2016). Risk of acute liver injury associated with use of antibiotics. Comparative cohort and nested case-control studies using two primary care databases in Europe. Pharmacoepidemiology and drug safety, 25 Suppl 1, 29–38. https://doi.org/10.1002/pds.3861
Baladé Martínez, L., Montero Corominas, D., & Macías Saint-Gerons, D. (2016). Uso del tratamiento hormonal sustitutivo en España: tendencias en el período 2000-2014 [Utilization of hormone replacement therapy in Spain: Trends in the period 2000-2014].
Medicina clínica, 147(7), 287–292.
https://doi.org/10.1016/j.medcli.2016.05.023
Macías Saint-Gerons, D., Huerta Álvarez, C., García Poza, P., Montero Corominas, D., & de la Fuente Honrubia, C. (2018). Trazodone utilization among the elderly in Spain. A population based study.
Revista de psiquiatría y salud mental, 11(4), 208–215.
https://doi.org/10.1016/j.rpsm.2016.11.003
2015
León Vázquez, F., Bonis, J., Bryant Cerezo, V., Herrero Hernández, S., Jamart Sánchez, L., & Díaz Holgado, A.. (2015). Prevención de fractura osteoporótica en España: uso de fármacos antes y después de una fractura de cadera.
Revista de Osteoporosis y Metabolismo Mineral, 7(2), 54-62.
https://dx.doi.org/10.4321/S1889-836X2015000200003
Sáez-Jiménez, Rafael, & Bonis, Julio. (2015). Estudio descriptivo sobre el uso de antiinflamatorios no esteroideos por vía intramuscular para el tratamiento de la lumbalgia aguda en las consultas de Atención Primaria en España durante 2002-2011.
Revista Clínica de Medicina de Familia, 8(2), 103-109.
https://dx.doi.org/10.4321/S1699-695X2015000200003
Souverein, P. C., Abbing-Karahagopian, V., Martin, E., Huerta, C., de Abajo, F., Leufkens, H. G., Candore, G., Alvarez, Y., Slattery, J., Miret, M., Requena, G., Gil, M. J., Groenwold, R. H., Reynolds, R., Schlienger, R. G., Logie, J. W., de Groot, M. C., Klungel, O. H., van Staa, T. P., Egberts, T. C., … Gardarsdottir, H. (2016). Understanding inconsistency in the results from observational pharmacoepidemiological studies: the case of antidepressant use and risk of hip/femur fractures.
Pharmacoepidemiology and drug safety, 25 Suppl 1, 88–102.
https://doi.org/10.1002/pds.3862
Macías Saint-Gerons, Diego & de la Fuente, César & Andrés-Trelles, Fernando & Catalá-López, Ferrán. (2014). Prevención primaria de las enfermedades cardiovasculares con estatinas en pacientes con diabetes.
Medicina Clínica. 144.
https://doi.org/10.1016/j.medcli.2014.05.001
García-Poza, P., de Abajo, F. J., Gil, M. J., Chacón, A., Bryant, V., & García-Rodríguez, L. A. (2015). Risk of ischemic stroke associated with non-steroidal anti-inflammatory drugs and paracetamol: a population-based case-control study.
Journal of thrombosis and haemostasis : JTH, 13(5), 708–718.
https://doi.org/10.1111/jth.12855
Rottenkolber, M., Voogd, E., van Dijk, L., Primatesta, P., Becker, C., Schlienger, R., de Groot, M. C., Alvarez, Y., Durand, J., Slattery, J., Afonso, A., Requena, G., Gil, M., Alvarez, A., Hesse, U., Gerlach, R., Hasford, J., Fischer, R., Klungel, O. H., & Schmiedl, S. (2015). Time trends of period prevalence rates of patients with inhaled long-acting beta-2-agonists-containing prescriptions: a European comparative database study.
PloS one, 10(2), e0117628.
https://doi.org/10.1371/journal.pone.0117628
De Abajo F, Gil Miguel, García-Poza Patricia, Alvarez Arturo, Bryant Verónica, García-Rodríguez, Luis. Allopurinol use is associated with a decrease in the risk of non-fatal acute myocardial infarction: evidence from a nested case-control study.
Heart 2015: 101; 679-685.
http://dx.doi.org/10.1136/heartjnl-2014-306670
Diego Macías Saint-Gerons, César de la Fuente Honrubia, Diana González Bermejo, Dolores Montero, Miguel J Gil, Antonio Salvador Sanz, Fernando de Andrés-Trelles y Ferrán Catalá-López. Utilización de la terapia intensiva con estatinas en la prevención secundaria de enfermedad vascular en España. Rev Esp Salud Pública 2015;89: 159-171.
http://scielo.isciii.es/scielo.php?script=sci_abstract&pid=S1135-57272015000200005
de Hoyos-Alonso, M., Bonis, J., Bryant, V., Castell Alcalá, M. V., & Otero Puime, Á. (2016). Calidad del registro del diagnóstico de demencia en atención primaria. La situación en España en el periodo 2002-2011 [Quality of registration of dementia diagnosis in primary care: The situation in Spain in 2002-2011].
Atención primaria, 48(1), 33–41.
https://doi.org/10.1016/j.aprim.2015.03.002
Rottenkolber, M., Voogd, E., van Dijk, L., Primatesta, P., Becker, C., de Groot, M. C., Plana, E., Alvarez, Y., Durand, J., Slattery, J., Afonso, A., Requena, G., Huerta, C., Alvarez, A., de Abajo, F., Tauscher, M., Hasford, J., Fischer, R., Reynolds, R., & Schmiedl, S. (2015). Seasonal changes in prescribing of long-acting beta-2-agonists-containing drugs.
Respiratory medicine, 109(7), 828–837.
https://doi.org/10.1016/j.rmed.2015.01.010
Sabaté, M., Ferrer, P., Ballarín, E., Rottenkolber, M., Amelio, J., Schmiedl, S., Reynolds, R., Klungel, O., Ibáñez, L., & PROTECT Work Package 2 (2015). Inpatient drug utilization in Europe: nationwide data sources and a review of publications on a selected group of medicines (PROTECT project).
Basic & clinical pharmacology & toxicology, 116(3), 201–211.
https://doi.org/10.1111/bcpt.12358
2014
Ruigómez, A., Brauer, R., Rodríguez, L. A., Huerta, C., Requena, G., Gil, M., de Abajo, F., Downey, G., Bate, A., Tepie, M. F., de Groot, M., Schlienger, R., Reynolds, R., & Klungel, O. (2014). Ascertainment of acute liver injury in two European primary care databases. European journal of clinical pharmacology, 70(10), 1227–1235. https://doi.org/10.1007/s00228-014-1721-y
Requena, G., Abbing-Karahagopian, V., Huerta, C., De Bruin, M. L., Alvarez, Y., Miret, M., Hesse, U., Gardarsdottir, H., Souverein, P. C., Slattery, J., Schneider, C., Rottenkolber, M., Schmiedl, S., Gil, M., De Groot, M. C., Bate, A., Ruigómez, A., García Rodríguez, L. A., Johansson, S., de Vries, F., … de Abajo, F. J. (2014). Incidence rates and trends of hip/femur fractures in five European countries: comparison using e-healthcare records databases.
Calcified tissue international, 94(6), 580–589.
https://doi.org/10.1007/s00223-014-9850-y
Abbing-Karahagopian, V., Kurz, X., de Vries, F., van Staa, T. P., Alvarez, Y., Hesse, U., Hasford, J., Dijk, L. v., de Abajo, F. J., Weil, J. G., Grimaldi-Bensouda, L., Egberts, A. C., Reynolds, R. F., & Klungel, O. H. (2014). Bridging differences in outcomes of pharmacoepidemiological studies: design and first results of the PROTECT project.
Current clinical pharmacology, 9(2), 130–138.
https://doi.org/10.2174/1574884708666131111211802
de Groot, M. C., Schuerch, M., de Vries, F., Hesse, U., Oliva, B., Gil, M., Huerta, C., Requena, G., de Abajo, F., Afonso, A. S., Souverein, P. C., Alvarez, Y., Slattery, J., Rottenkolber, M., Schmiedl, S., Van Dijk, L., Schlienger, R. G., Reynolds, R., & Klungel, O. H. (2014). Antiepileptic drug use in seven electronic health record databases in Europe: a methodologic comparison.
Epilepsia, 55(5), 666–673.
https://doi.org/10.1111/epi.12557
Abbing-Karahagopian, V., Huerta, C., Souverein, P. C., de Abajo, F., Leufkens, H. G., Slattery, J., Alvarez, Y., Miret, M., Gil, M., Oliva, B., Hesse, U., Requena, G., de Vries, F., Rottenkolber, M., Schmiedl, S., Reynolds, R., Schlienger, R. G., de Groot, M. C., Klungel, O. H., van Staa, T. P., … De Bruin, M. L. (2014). Antidepressant prescribing in five European countries: application of common definitions to assess the prevalence, clinical observations, and methodological implications.
European journal of clinical pharmacology, 70(7), 849–857.
https://doi.org/10.1007/s00228-014-1676-z
de Abajo, F. J., Gil, M. J., García Poza, P., Bryant, V., Oliva, B., Timoner, J., & García-Rodríguez, L. A. (2014). Risk of nonfatal acute myocardial infarction associated with non-steroidal antiinflammatory drugs, non-narcotic analgesics and other drugs used in osteoarthritis: a nested case-control study.
Pharmacoepidemiology and drug safety, 23(11), 1128–1138.
https://doi.org/10.1002/pds.3617
2013
Macías Saint-Gerons, D., de la Fuente Honrubia, C., Montero Corominas, D., Gil, M. J., de Andrés-Trelles, F., & Catalá-López, F. (2014). Standard and intensive lipid-lowering therapy with statins for the primary prevention of vascular diseases: a population-based study.
European journal of clinical pharmacology, 70(1), 99–108.
https://doi.org/10.1007/s00228-013-1586-5
Bonis J , de Hoyos MC, Llorente A, Gil M, Montero D, de Abajo FJ. Prevalencia de uso de fármacos para el tratamiento de la enfermedad de Alzheimer y su evolución temporal: un estudio descriptivo con la base de datos de atención primaria BIFAP.
Alzheimer. Realidades e Investigación en Demencia 2013;54:20-27.
https://doi.org/10.5538/1137-1242.2013.54.20
Erviti, J., Alonso, A., Gorricho, J., & López, A. (2013). Oral bisphosphonates may not decrease hip fracture risk in elderly Spanish women: a nested case-control study.
BMJ open, 3(2), e002084.
https://doi.org/10.1136/bmjopen-2012-002084
Erviti, J., Alonso, A., Oliva, B., Gorricho, J., López, A., Timoner, J., Huerta, C., Gil, M., & De Abajo, F. (2013). Oral bisphosphonates are associated with increased risk of subtrochanteric and diaphyseal fractures in elderly women: a nested case-control study.
BMJ open, 3(1), e002091.
https://doi.org/10.1136/bmjopen-2012-002091
2012
de Abajo, F. J., Gil, M. J., Bryant, V., Timoner, J., Oliva, B., & García-Rodríguez, L. A. (2013). Upper gastrointestinal bleeding associated with NSAIDs, other drugs and interactions: a nested case-control study in a new general practice database. European journal of clinical pharmacology, 69(3), 691–701.
https://doi.org/10.1007/s00228-012-1386-3
2011
Gil, M., Oliva, B., Timoner, J., Maciá, M. A., Bryant, V., & de Abajo, F. J. (2011). Risk of meningioma among users of high doses of cyproterone acetate as compared with the general population: evidence from a population-based cohort study.
British journal of clinical pharmacology, 72(6), 965–968.
https://doi.org/10.1111/j.1365-2125.2011.04031.x
2010
Chacón García, A., Ruigómez, A., & García Rodríguez, L. A. (2010). Incidencia de neumonía adquirida en la comunidad en la cohorte poblacional de la base de datos en atención primaria (BIFAP) [Incidence rate of community acquired pneumonia in a population cohort registered in BIFAP].
Atención primaria, 42(11), 543–549.
https://doi.org/10.1016/j.aprim.2010.05.004
2006
Hernández-Díaz, S., & García Rodríguez, L. A. (2006). Cardioprotective aspirin users and their excess risk of upper gastrointestinal complications.
BMC medicine, 4, 22.
https://doi.org/10.1186/1741-7015-4-22
2004
de Abajo FJ, García Rodríguez LA. Consumo de ácido acetilsalicílico en pacientes con diabetes mellitus (letter). Med Clin 2004;123:236-9.
2002
Salvador Rosa, A., Moreno Pérez, J. C., Sonego, D., García Rodríguez, L. A., & de Abajo Iglesias, F. J. (2002). El Proyecto BIFAP: Base de datos para la Investigación Farmacoepidemiológica en Atención Primaria [The BIFAP project: database for pharmaco-epidemiological research in primary care].
Atención primaria, 30(10), 655–661.
https://doi.org/10.1016/s0212-6567(02)79129-4
